abstract：:During the development of the mammalian inner ear, the number of hair cells produced is highly regulated and remains constant throughout life. The mechanism underlying this regulation is beginning to be understood although many aspects still remain obscure. When late embryonic or early postnatal rat organs of Corti we...

journal_title：Acta oto-laryngologica

authors： Lefebvr PP,Malgrange B,Thiry M,Breuskin I,Van De Water TR,Moonen G

更新日期：2001-01-01 00:00:00

abstract：:The influence of neck and leg proprioceptive inputs on optokinetic-induced quick phases was studied in humans. Ten subjects received unidirectional horizontal optokinetic stimulation (10-20%/s) during sinusoidal neck, leg and combined neck + leg proprioceptive stimulation. The optokinetic reflex was measured by electr...

journal_title：Acta oto-laryngologica

authors： Botti F,Anastasopoulos D,Kostadima V,Bambagioni D,Pettorossi VE

更新日期：2001-01-01 00:00:00

abstract：:A questionnaire was devised to quantify and measure four categories: the behavioral characteristics of Type A, self-restraint and escape; the causes of anxiety; means of relaxation; and symptoms incidental to anxiety. Questionnaire analysis was performed in patients (n = 60) with Meniere's disease and in a control pop...

journal_title：Acta oto-laryngologica

authors： Takahashi M,Ishida K,Iida M,Yamashita H,Sugawara K

更新日期：2001-01-01 00:00:00

abstract：:Recent investigations of children with specific language impairment (SLI) have found deviant anatomical asymmetry of the perisylvian cortex. These studies argue that this deviant anatomical asymmetry is linked to the language disorders of SLI children. To date no studies have examined whether deviant functional asymme...

journal_title：Acta oto-laryngologica

authors： Shafer VL,Schwartz RG,Mor ML,Kessler KL,Kurtzberg D,Ruben RJ

更新日期：2001-01-01 00:00:00

abstract：:Immunological mechanisms are thought to play an important role in the pathogenesis of some cochleo-vestibular diseases. This study attempts to present further evidence of autoantibodies reactive against guinea pig inner ear proteins found in patients with autoimmune inner ear diseases (AIED) and specifically identifie...

journal_title：Acta oto-laryngologica

authors： Boulassel MR,Deggouj N,Tomasi JP,Gersdorff M

更新日期：2001-01-01 00:00:00

abstract：:Macrolides have been used for decades as an important chemotherapeutic agent in the treatment of infectious diseases. In the last 10 years there has also been increasing interest in the interaction between macrolide antibiotics and the immune system. The aim of this review is to focus on the anti-inflammatory action o...

journal_title：Acta oto-laryngologica

authors： Cervin A

更新日期：2001-01-01 00:00:00

abstract：:Cisplatin and gentamicin are two ototoxicants that are supposed to be transported by the paracellar route, i.e. via cellular junctions, to the perilymphatic compartment. This study was initiated to test the hypothesis that susceptive variation of individuals to ototoxic drugs may be explained by variability in transpo...

journal_title：Acta oto-laryngologica

authors： Laurell G,Viberg A,Teixeira M,Sterkers O,Ferrary E

更新日期：2000-10-01 00:00:00

abstract：:We report a case of electromagnetic interference between a bone-anchored hearing aid (BAHA) and a cellular phone. A 54-year-old women was successfully treated for severe mixed conductive and sensorineural hearing loss with a BAHA. Five years after implantation, the patient experienced a sudden feeling of dizziness, ac...

journal_title：Acta oto-laryngologica

authors： Kompis M,Negri S,Häusler R

更新日期：2000-10-01 00:00:00

abstract：:Tumour growth of vestibular schwannomas is still difficult to predict. The aim of our study was to determine whether any defined histopathological feature was correlated with the clinical course. We did a retrospective study with 69 paraffin-embedded tumours to establish whether the number of vessels, blood cells extr...

journal_title：Acta oto-laryngologica

authors： Labit-Bouvier C,Crebassa B,Bouvier C,Andrac-Meyer L,Magnan J,Charpin C

更新日期：2000-10-01 00:00:00

abstract：:We studied the influence of neck afferents on the perception of orientation. In Experiment 1, we investigated the effect of head tilt on the subjective vertical in both the visual and tactile modalities. The results showed that head tilt triggers an Aubert effect in the visual modality and a Müller effect in the tacti...

journal_title：Acta oto-laryngologica

authors： Guerraz M,Luyat M,Poquin D,Ohlmann T

更新日期：2000-09-01 00:00:00

abstract：:The expression of vascular cell adhesion molecule-1 (VCAM-1), alpha4-integrin and L-selectin was dynamically observed using an immunohistochemical approach during labyrinthitis induced by inoculation of keyhole limpet hemocyanin into the scala tympani of animals that had been systemically sensitized to it. At the same...

journal_title：Acta oto-laryngologica

authors： Zhang C,Huang W,Song H

更新日期：2000-08-01 00:00:00

abstract：:We recently reported the development of a cell line, AMC-HN-9, established from an undifferentiated carcinoma (UDC) of the parotid gland. AMC-HN-9 consists mostly of spindle-shaped cells, has poor in vitro adhesiveness and an in vitro appearance that is different from that of other epithelial cell lines. To test the h...

journal_title：Acta oto-laryngologica

authors： Kim SH,Carey TE,Liebert M,Yoo SJ,Kwon HJ,Kim SY

更新日期：2000-08-01 00:00:00

abstract：:This study combined ultrastructural and statistical methods to learn the effects of weightlessness on rat utricular maculae. A principle aim was to determine whether weightlessness chiefly affects ribbon synapses of type II cells, since the cells communicate predominantly with branches of primary vestibular afferent e...

journal_title：Acta oto-laryngologica

authors： Ross MD

更新日期：2000-06-01 00:00:00

abstract：:Primary non-Hodgkin's lymphoma of the nasal cavity is a disease more likely to affect men than women; it is characterized by a T cell immunophenotype and is often associated with involvement of the paranasal structures and with high recurrence rates. Many authors report that its extremely poor prognosis depends on tum...

journal_title：Acta oto-laryngologica

authors： Cavalot AL,Ricci E,Nazionale G,Palonta F,Fadda GL

更新日期：2000-06-01 00:00:00

abstract：:Cisplatin ototoxicity is known to involve mainly the organ of Corti. Outer hair cells (OHCs). especially in the basal turn, are preferentially involved. One possible mechanism of ototoxicity might be alteration of the antioxidant system causing an increase in free radicals. It has been demonstrated that heat shock pro...

journal_title：Acta oto-laryngologica

authors： Oh SH,Yu WS,Song BH,Lim D,Koo JW,Chang SO,Kim CS

更新日期：2000-03-01 00:00:00

abstract：:In electrocochleography (ECochG) compound action potential (CAP) and summation potential (SP) are usually separated from the cochlear microphonic (CM) by the CM cancellation technique consisting in averaging the responses evoked by rarefaction and condensation clicks. With the aim of analysing the ECochG responses evo...

journal_title：Acta oto-laryngologica

authors： Arslan E,Santarelli R,Sparacino G,Sella G

更新日期：2000-03-01 00:00:00

abstract：:The effects of two simulated hearing impairments (presbyacusis) on speech perception were investigated in two groups of normally hearing subjects (30 and 48 subjects, respectively). Eight patients with presbyacusis with similar hearing impairment to those in the latter simulation served as the clinical material. Word ...

journal_title：Acta oto-laryngologica

authors： Sorri M,Huttunen K,Körkkö P,Mäki-Torkko E

更新日期：2000-03-01 00:00:00

abstract：:Scleroma, chronic specific granuloma of the nose and upper respiratory tract, is endemic in Egypt and many other countries. The exact pathogenesis of the disease as regards the aetiological role of Klebsiella rhinoscleromatis is contradictory. This work investigated the effect of experimental intravenous injection of ...

journal_title：Acta oto-laryngologica

authors： Gaafar HA,Bassiouny M,El Mofty M,Badour NM,Nour YA

更新日期：2000-03-01 00:00:00

abstract：:Recent studies have implicated nitric oxide (NO) in neuronal degeneration and plasticity in the motor nervous system. In the present study, we investigated the induction of nitric oxide synthase (NOS) in the motoneurons in the nucleus ambiguus (NA) after injury to the rat recurrent laryngeal nerve (RLN) using nicotina...

journal_title：Acta oto-laryngologica

authors： Bamba H,Uno T,Koike S,Shogaki K,Hisa Y

更新日期：2000-03-01 00:00:00

abstract：:In the present study, the protective effect of dexamethasone was analysed following exposure of the cochlea to Pseudomonas aeruginosa Exotoxin A (PaExoA). Four groups of albino Sprague-Dawley rats were used. 20 microl saline was instilled through the tympanic membrane into the round window niche (group A, n = 4); 1 mi...

journal_title：Acta oto-laryngologica

authors： Takeuchi N,Anniko M

更新日期：2000-03-01 00:00:00

abstract：:The gas nitric oxide (NO) is present in high concentrations in human nasal airways. Since NO is known to inhibit the growth of bacteria and viruses, it has been suggested that airborne NO represents the first line of defence against pathogens in the upper airways. Low nasal NO levels have been reported previously in p...

journal_title：Acta oto-laryngologica

authors： Palm J,Lidman C,Graf P,Alving K,Lundberg J

更新日期：2000-03-01 00:00:00

abstract：:Cells can die by two distinct pathways: apoptosis and necrosis. To explore whether intense noise can induce hair cell (HC) death via the apoptotic pathway, we systematically examined morphological changes in guinea pig cochlear HC nuclei stained with Hoechst 33342, a fluorescent dye specifically labelling the nuclear ...

journal_title：Acta oto-laryngologica

authors： Hu BH,Guo W,Wang PY,Henderson D,Jiang SC

更新日期：2000-01-01 00:00:00

abstract：:Endoscopy is needed for reliable evaluation of the treatment of nasal polyposis. In this study, we compared the reproducibility of various score systems for staging nasal polyposis and the inter-individual variations between investigators. The mass of the polyps was assessed by five methods, three new techniques (numb...

journal_title：Acta oto-laryngologica

authors： Johansson L,Akerlund A,Holmberg K,Melén I,Stierna P,Bende M

更新日期：2000-01-01 00:00:00

abstract：:In this study auditory brainstem responses (ABRs) were recorded repeatedly in three awake cats before and after bilateral aspiration of the inferior colliculi (ICs). All surgical procedures were performed under anaesthesia with Nembutal. Postoperative recordings were obtained 1 week, 3 months, 8 months and 13 months a...

journal_title：Acta oto-laryngologica

authors： Kaga K,Yamada K,Tsuzuku T,Uno A

更新日期：1999-03-01 00:00:00

abstract：:The efferent cochlear system, composed of both ipsi- and contralateral bundles, runs along with the vestibular nerve and may serve as protection for the inner ear. Sectioning of the vestibular nerve could thus create an experimental model for further in-depth study of such a protective role. A personal surgical approa...

journal_title：Acta oto-laryngologica

authors： Barbara M,Attanasio G,Piccoli F,Filipo R

更新日期：1999-03-01 00:00:00

abstract：:Detailed longitudinal studies of speech perception, speech production and language acquisition have justified a significant change in the demographics of congenitally and prelingually deaf children who receive cochlear implants. A trend toward earlier cochlear implantation has been justified by improvements in measure...

journal_title：Acta oto-laryngologica

authors： Miyamoto RT,Kirk KI,Svirsky MA,Sehgal ST

更新日期：1999-03-01 00:00:00

abstract：:Fibroblasts in two portions of the vocal fold mucosa, the macula flava (MF) and Reinke's space (RS), were investigated by means of transmission electron microscopy. Five adult and five newborn larynges from autopsy cases were subjected to study. Both in adults and newborns, fibroblasts in the MF tended to be stellate ...

journal_title：Acta oto-laryngologica

authors： Hirano M,Sato K,Nakashima T

更新日期：1999-03-01 00:00:00

abstract：:This study aimed to investigate whether unilateral vestibular neuritis (VN) causes the same deficits of ocular counter-roll during static head roll (OCR(S)) and dynamic vestibulo-ocular reflex gains during head impulses (VOR(HI)) as unilateral vestibular deafferentation (VD). Ten patients with acute and 14 patients wi...

journal_title：Acta oto-laryngologica

authors： Schmid-Priscoveanu A,Straumann D,Böhmer A,Obzina H

更新日期：1999-01-01 00:00:00

abstract：:Nasal polyps is a chronic inflammatory disease of the upper airway characterized by structural abnormalities including stromal fibrosis. Fibroblasts are a rich source of cytokines and inflammatory mediators and are thought to play an important role in the development of fibrosis. In addition, there is considerable evi...

journal_title：Acta oto-laryngologica

authors： Nonaka M,Pawankar R,Saji F,Yagi T

更新日期：1999-01-01 00:00:00

abstract：:Seven to eight years after a disease period of vestibular neuritis 19 patients previously examined at our department were given a questionnaire about whether they had experienced any audiovestibular symptoms since they first fell ill. All 19 patients responded and 18 consented to participate in the long-term follow-up...

journal_title：Acta oto-laryngologica

authors： Bergenius J,Perols O

更新日期：1999-01-01 00:00:00

abstract：:Urokinase-type plasminogen activator (uPA) is important for matrix degradation and motility of cancer cells. The binding of uPA to its cell surface receptor on cancer cells is essential for effective invasion. A soluble form of urokinase receptor (suPAR) has been described in serum and ascites of ovarian cancer patien...

journal_title：Acta oto-laryngologica

authors： Schmidt M,Hoppe F

更新日期：1999-01-01 00:00:00

abstract：:We have developed a new technique for analyzing the rotation vector of eye movement in three dimensions with an infrared CCD camera based on the following four assumptions; i) the eye rotates on a point; ii) the pupil edge is a circle; iii) the distance from the center of eye rotation to pupil circle remains unchanged...

journal_title：Acta oto-laryngologica

authors： Imai T,Takeda N,Morita M,Koizuka I,Kubo T,Miura K,Nakamae K,Fujioka H

更新日期：1999-01-01 00:00:00

abstract：:The trachea whole organ perfusion technique was used to study the effect of tumor necrosis factor alpha (TNF alpha) and interleukin-1 alpha (IL-1 alpha) on the adherence of otitis media pathogen Streptococcus pneumoniae (Spn) type 6A. Tracheas were removed from chinchillas and divided equally. One-half trachea was act...

journal_title：Acta oto-laryngologica

authors： Tong HH,Fisher LM,Kosunick GM,Demaria TF

更新日期：1999-01-01 00:00:00

abstract：:Evaluation of some 200 endolymph proteins indicates that they are predominantly derived from plasma. However, the profile of endolymph proteins is remarkably similar to that of perilymph and entirely different from that of plasma. This supports the current consensus that perilymph rather than plasma is the (direct) so...

journal_title：Acta oto-laryngologica

authors： Thalmann R,Thalmann I

更新日期：1999-01-01 00:00:00

abstract：:Volumetric changes of the scala media were histologically investigated in normal guinea pigs to see whether glycerol-induced volumetric change of the scala media followed a biphasic course similar to the auditory threshold in the glycerol test. Glycerol was administered orally in a 12 ml/kg dose. The volume of the sca...

journal_title：Acta oto-laryngologica

authors： Takeda T,Takeda S,Saito H,Hamada M,Sawada S

更新日期：1999-01-01 00:00:00

abstract：:The objective of this study was to examine the outcome of unilateral stapes surgery in one patient group with bilateral hearing loss and one group with unilateral hearing loss. The patients' own estimations of improvement in hearing ability and the occurrence of other ear-related symptoms were examined retrospectively...

journal_title：Acta oto-laryngologica

authors： Lundman L,Mendel L,Bagger-Sjöbäck D,Rosenhall U

更新日期：1999-01-01 00:00:00

abstract：:This study correlates static and flow-cytometric analysis on paraffin-embedded and fresh material of salivary gland carcinomas. Nuclear suspensions for DNA analysis were prepared from paraffin-embedded and fresh material. Comparison of the results of static and flow cytometry on paraffin-embedded material revealed no ...

journal_title：Acta oto-laryngologica

authors： Nordgård S,Franzén G,Boysen M,Tytor M

更新日期：1999-01-01 00:00:00

abstract：:We previously reported that long-term exposure to glutamate (Glu) induced death of cochlear outer hair cells (OHCs). However, the mechanisms of OHC death induced by Glu were unclear. In the central nervous system, Glu is known to interfere with a cystine-Glu antiporter, leading to a decrease in cystine uptake and redu...

journal_title：Acta oto-laryngologica

authors： Sunami K,Yamane H,Takayama M,Nakagawa T,Konishi K,Iguchi H

更新日期：1999-01-01 00:00:00

abstract：:The distribution of vascular endothelial growth factor (VEGF), one of the most important angiogenic factors, and microvessel density (MVD) were assessed in laryngeal carcinomas by means of immunohistochemistry. Correlation of VEGF with MVD and clinical parameters (T stage, N stage, histological grading, survival, recu...

journal_title：Acta oto-laryngologica

authors： Neuchrist C,Quint C,Pammer A,Burian M

更新日期：1999-01-01 00:00:00

abstract：:The objective of this study was to develop and test an endolabyrinthic microsurgical procedure for treatment of vertigo, the utriculostomy. This involves the application of local heat for obtaining a fistula in the membranous labyrinth, so as to establish communication between the endolymphatic and perilymphatic space...

journal_title：Acta oto-laryngologica

authors： Lavinsky L,Goycoolea M,Gananca MM,Zwetsch Y

更新日期：1999-01-01 00:00:00